Bovine tuberculosis (TB) is a chronic disease of animals caused by a bacterium called Mycobacterium bovis (M. bovis), which is closely related to the bacteria causing human and avian tuberculosis. It can affect practically all mammals, in which it causes a deterioration of the general state of health, very often cough and, in the long run, death.

The name «Tuberculosis» comes from the nodules, called «tubers», which are form in the lymph nodes of the affected animal. Until the 1920s, when control measures began to be applied in the countries developed, was one of the main diseases of domestic animals in all the world. Today, bovine tuberculosis remains an important disease of cattle and wildlife. It is also an important Zoonosis (animal disease that can be transmitted to humans).

TB is one of the diseases listed in the Animal Health Code Terrestrials of the World Organization for Animal Health (OIE) as conditions of mandatory notification to the OIE, in accordance with the OIE Terrestrial Animal Health Code (

The NATIONAL HEALTH SERVICE of Costa Rica – SENASA, entity attached to the Ministry of Agriculture and Livestock – MAG, which is in charge of the Epidemiological Surveillance Program of this disease, specifically in its head Dr. Julio César Jiménez DVM, has considered redouble efforts at the national level to achieve the Control and Eradication of this disease that, in addition to the risks it represents for human health, brings great losses for the producer.

Therefore,  the Ph.D. Jacobus H. de Waard was contacted, scientist recognized worldwide, to perform an advisory in order to validate the diagnostic test by means of the Interferon gamma technique, and to refine details about the primary diagnosis processes (Animal Tuberculinization), as a way to assure the producer that the animals that are positive are with a high degree of certainty (Sensitivity) carriers of the disease.

BIOADVANCE®, ID.Vet Labs., and the College of Veterinary Physicians of Costa Rica-COLVET, joined this activity, achieving a resounding success in the objectives set by all SENASA authorities.

Activities were carried out in the field, and in the Laboratory, as well as a Conference for all the Official Veterinarians for the realization of the field diagnostic tests.

To see the conference, go to the link:

We thank Dr. De Waard for his invaluable cooperation, his contribution to simplifying processes, and placing Costa Rica at the forefront of the fight against this complex disease.

More info in: